What's next for STORM-seq?

In collaboration with Takara Bio and SPT Labtech, we are adding unique molecular identifiers (UMIs) into the mix, as well as some spike-in controls. What originally sparked the development of STORM-seq was the desire to profile the entire transcriptome combined with a multi-omic profile through orthogonal measurements using ATAC-seq or bisulfite sequencing of a single cell. We're working on this [...]

What's next for STORM-seq?

In collaboration with Takara Bio and SPT Labtech, we are adding unique molecular identifiers (UMIs) into the mix, as well as some spike-in controls. What originally sparked the development of STORM-seq was the desire to profile the entire transcriptome combined with a multi-omic profile through orthogonal measurements using ATAC-seq or bisulfite sequencing of a single cell. We're working on this [...]

Does compartmap only work with STORM-seq?

Compartmap also works with single-cell RNA-seq, single-cell ATAC-seq, and whole genome bisulfite sequencing of single cells. It also works with methylation arrays. Beyond that, there are a variety of different single-cell profiling approaches that compartmap is compatible with to provide higher-order chromic confirmation.SMART-Seq Stranded [...]

Does compartmap only work with STORM-seq?

Compartmap also works with single-cell RNA-seq, single-cell ATAC-seq, and whole genome bisulfite sequencing of single cells. It also works with methylation arrays. Beyond that, there are a variety of different single-cell profiling approaches that compartmap is compatible with to provide higher-order chromic confirmation.SMART-Seq Stranded [...]

Have you looked at repeat space since you're looking at total RNA (e.g., ERVs, etc.)?

We are in the process of looking at repeat space because we have 2 x 100 reads and are probing the total transcriptome. We don't have data to share yet, but STORM-seq could prove useful in looking at this information. SMART-Seq Stranded [...]