Why is Tet system approved fetal bovine serum necessary?
Why is Tet system approved fetal bovine serum necessary?
With the greatly increased sensitivity of the Tet-On 3G systems, it is more important than ever that the serum you use for your studies is tetracycline-free. Only Takara Bio performs actual inducibility tests on a sensitive Tet-inducible cell line in order to provide an absolute guarantee that your serum is tetracycline-free.
Why is this necessary?
Cattle are routinely fed tetracyclines to guard against infection and build muscle mass. Any residual tetracyclines in serum will increase the basal expression from our highly sensitive Tet-On 3G systems. Only fetal bovine serum from Takara Bio is functionally tested to guarantee consistent results with tetracycline-inducible expression systems.
![](https://www.takarabio.com/images/360-Tet/CC-TechFigs/GFXN_AC_Tet_System_FBS_575x275.jpg)