What are the features of different AAV serotypes?
What are the features of different AAV serotypes?
Serotype is classified by the type of capsid structural proteins and determines tissue specificity. Serotype 2 (AAV2) is the most well-studied serotype. AAV2 has a broad range of tissue infectivity and is the most popular serotype for research purposes. Serotype 5 (AAV5) and serotype 6 (AAV6) have more specific tissue infectivity; AAV5 can infect cells in tissues including the central nervous system, liver, and retina, whereas AAV6 can infect cells in tissues including heart, muscle, and liver.
We currently offer products for production, purification, and titration of AAV2 for gene delivery.