What features of AAV makes the virus a good vector for gene delivery?
What features of AAV makes the virus a good vector for gene delivery?
AAV vectors exploit the properties of AAV for transduction of genes to cells and organisms. AAV vectors are generally considered safer than adenoviral and retroviral vectors. AAV vectors can be used to transduce genes into both proliferating and nonproliferating cells and can impart long-term expression in nondividing cells. In addition, AAV has little immunogenicity and is suitable for the transduction of genes into animals (as an in vivo transduction tool).