I observe dome-like structures in Cellartis enhanced hiPS-HEP cell culture. Is this normal?
I observe dome-like structures in Cellartis enhanced hiPS-HEP cell culture. Is this normal?
Occasionally, these domes appear, but they do not affect overall cell performance. In these structures, the hepatocytes have detached from the coating, possibly because they were growing very densely. To prevent cell loss, please be careful when changing the media; always leave 10% of the media in each well.
![Dome-like structure in Cellartis hiPS-HEP cell culture](https://www.takarabio.com/images/600-Stem_Cell_Research/CC-TechFigs/CELLQA_FAQ02_103916.jpg)