What is p24 in Lentiviral titration kits?
What is p24 in Lentiviral titration kits?
| Recombinant lentiviruses generated for research use contain major structural proteins, including envelope proteins, matrix proteins, and virus core proteins. p24 is a structural protein that comprises a majority of the capsid (or shell) of lentiviral particles, and is encoded by the gag gene (along with the nucleocapsid proteins, p6 and p7, and the matrix protein, p17). Lenti‑X GoStix Plus and methods such as p24 ELISAs are designed to specifically measure the amount of p24 capsid protein present in lentiviral supernatants, because levels of p24 correlate directly with infectious viral titer. |